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Roger Rubio Sanchez

Dr Roger Rubio Sánchez

BSc MRes PhD

  • Position Governing Body Fellow Junior Research Fellow
  • School Technology Department of Chemical Engineering and Biotechnology
  • Email rmr44@cam.ac.uk
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Roger is a BBSRC Discovery Research Fellow hosted at the Department of Chemical Engineering and Biotechnology and a Junior Research Fellow at Âé¶¹ËÞÉáµçÊÓ¾çCollege. Roger's work focuses on exploiting the tools of DNA nanotechnology to elucidate new biophysical principles for membrane signalling and bio-engineering cell-like agents for healthcare and biomedicine.

Roger Rubio Sanchez

Roger completed his BSc in Biotechnology Engineering at the Instituto Tecnológico y de Estudios Superiores de Monterrey in Mexico City (2015). He moved to Cambridge UK in 2017 to read for an MRes in Nanoscience and Nanotechnology as part of the Centre for Doctoral Training NanoDTC programme, through which he then obtained a PhD in Physics from the Cavendish Laboratory (2021). He continued his research through two postdoctoral appointments, first at Imperial College London (Department of Chemistry) and later back at the University of Cambridge (Department of Chemical Engineering and Biotechnology).

Roger's work has involved studying the biophysical principles that govern the spatial and temporal organisation of membranes, with the goal of constructing DNA nanostructures that could mimic the form and function of cell-surface machinery. By applying his membrane-active DNA nano-devices, Roger engineers advanced functionalities in synthetic cell-like objects, which are useful as models for fundamental research and hold great potential as next-generation biomedical platforms.

Since 2023, he has been an independent Research Fellow (BBSRC Discovery Fellow) hosted at the Department of Chemical Engineering and Biotechnology, University of Cambridge. Roger is also the coordinator and lecturer of the Bionanotechnology course, taught as part of the MRes in Nanoscience and Nanotechnology and MPhil in Micro and Nanotechnology Enterprise programmes.

Roger’s research interests follow the exciting goals, applications, and impact of synthetic cell science and engineering biology. Roger applies his expertise to advance the toolkit available to engineer synthetic cells and unlock their promised applications to biomedicine.

By applying the tools of amphiphilic DNA nanotechnology to lipid membranes and their phase behaviour, Roger´s work leads to the construction of synthetic cells with purposefully designed functionality. His bespoke DNA nanostructures can impart function to synthetic-cell lipid membranes so that these cell-like objects exhibit behaviours typically observed in living organisms, which can in turn allow synthetic cells to detect and respond to changes in their surroundings.

Exploiting these tailored and bio-mimetic DNA-membrane platforms, Roger designs synthetic cells with the ability to coordinate responses similar to immune cells. With his approach to constructing immune-like synthetic cells, Roger plans to unlock new pathways to detect and respond to the presence of pathogens, enabling the application of synthetic-cell biotechnologies for bottom-up immunity in healthcare and bio-medicine.

What's on

A triptych of abstract images: a smooth round stone nestled in a curved rock, distorted eyeglass frames scattered on a white background, and a high-contrast black and white microscopic image resembling organic or cellular structures.

Art Exhibition: Âé¶¹ËÞÉáµçÊÓ¾çat 60

21/06/2025 at 10.00

Celebrating Wolfson’s 60th anniversary year, this exhibition highlights the range of artistic disciplines and styles that have made up our exhibitions over the years.

A group of people stands outdoors near a table with books and papers, attentively reading or listening during a gathering.

WolfWords Launch and Poetry Reading

27/06/2025 at 11.00

Please come and join us for the launch of this year's WolfWords poetry anthologywhich brings together poems from the entire Âé¶¹ËÞÉáµçÊÓ¾çcommunity.

Âé¶¹ËÞÉáµçÊÓ¾çChampagne Credit Ian Olsson

Wolfson's 60th Birthday Party

27/06/2025 at 18.30

Come party like it's 1965 as we celebrate Wolfson's 60th birthday!

Graphic for "Cambridge Zero Community Day" on 28 June 2025 from 10:00 to 20:30, with the tagline "Forging a Future for Our Planet" and descriptors "Innovative, Inclusive, Impactful."

Cambridge Zero Community Day

28/06/2025 at 10.00

Âé¶¹ËÞÉáµçÊÓ¾çCollege will showcase its commitment to Sustainability and Conservation and Green Impact by exhibiting a number of projects around the College at the Cambridge Zero Community Day.

A large stone church with a tall spire and ornate Gothic-style windows stands on a grassy hill under a clear blue sky.

Thaxted Festival Mass

29/06/2025 at 11.00

Haydn’s delightful Little Organ Mass will be sung by Âé¶¹ËÞÉáµçÊÓ¾çChamber Singers, accompanied by the historic Lincoln Organ played by Tom Williamson.

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